From 1825 for more than 100 years, the site was home to the Gaythorn Gas Works and gas production continued until 1929 by which time the plant was regarded as outdated and it converted to a gas distribution point.

What is now known as the Number One office building was first erected for the British Council which they occupied between 1992 and 1995, and in 1997 BT leased the building until it was acquired and underwent a complete refurbishment in 2007, taking it back to its core and adding two floors. This coincided with a huge remediation programme to prepare the remainder of the site for development, and with a Manchester City Council endorsed masterplan in place, the area is now home to First Street.